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The plasma expresses minnesota timberwolves clearance ofCNS timberwolves displays 7056 was approximately three times more rapid than the clearance ofmidazolam. The pharmacokinetic profile of CNS 7056 was linear within the doserange examined Timberwolves tickets . PAION will now progress to the next stage of development and start seeking apartner for territories outside Japan in parallel to the commencement of PhaseII In Japan, CNS 7056 is partnered with Ono Pharmaceuticals. Wolfgang Söhngen, CEO of PAION commented: "The positive data meet ourexpectations. We are positive that CNS 7056 could be a valuable alternative forprocedural sedation by avoiding the potential for prolonged or overly deepsedation thus potentially reducing the intensity of supervision needed. We willseek ways to explore its potential also in other indications.

It was especiallyre-assuring to see that sedation, to the level of unconsciousness, could beachieved without safety concerns minesota timberwolves . PAION`s management and project team are proudto see that these results confirm our high expectations for the potential ofthis compound, which was in the pre-clinical development phase when we completedthe CeNeS acquisition last summer."Note: An updated company presentation including the new data on CNS 7056 will beavailable on starting Monday, 12 January 2009.About CNS 7056CNS 7056 is a new short-acting sedative and general anaesthetic that acts onGABAA receptors timberwolves basketball . The substance was added to PAION`s portfolio by acquiring CeNeSwho in turn had acquired the substance from GlaxoSmithKline t wolves Minnesota Timberwolves . CNS 7056 is awater-soluble, rapid and short-acting GABAA receptor modulator interacting withthe benzodiazepine site mark madsen . After intravenous administration to human volunteers,CNS 7056 rapidly induces sedation nba.com - timberwolves . Importantly the sedative effects rapidlydisappear after cessation of administration. The rapid offset of effect of thecompound is due to its metabolism by esterase enzymes that are widelydistributed throughout the body.

Therefore it is anticipated that CNS 7056 canbe clinically developed as a sedative agent for day case procedures, theinduction and maintenance of anaesthesia and as a sedative for mechanicalventilation in the Intensive Care Unit (ICU) minnesota timberwolves and lynx scholarship . In 2007, CeNeS completed a licenseagreement for CNS 7056 with Ono Pharmaceuticals lakers . Under this agreement, Ono willdevelop and commercialize CNS 7056 for the Japanese territory spurs . About PAIONPAION is a biopharmaceutical company headquartered in Aachen, Germany timberwolves gear . Since theacquisition of CeNeS Pharmaceuticals, which was completed in June 2008, thecompany has a second site in Cambridge, UK Minnesota Timberwolves tickets - nba Minnesota Timberwolves tickets . The company is specializing indeveloping and commercializing innovative drugs for the hospital-based treatmentof central nervous system (CNS) disorders and thrombotic/cardiovasculardiseases, indications for which there is a substantial unmet medical need. PAIONintends to further expand its portfolio of drugs by exploiting its coreexpertise in identifying high-potential compounds, licensing or otherwiseacquiring them and advancing them through the clinical development andregulatory approval process Minnesota Timberwolves - wikipedia .

Where appropriate, particularly during the latestages of the clinical development and approval process and thecommercialization phase, PAION seeks to collaborate with experienced partners PAION AGDr . Peer Nils SchröderDirector Corporate Communications & Investor RelationsPhone +49 241 4453-152E-mail orTeathersNomad and broker (AIM)Shaun Dobson/Claes SpångPhone +44 20 7131 3000 Copyright Business Wire 2009 timberwolves rumors . LOS ANGELES (Reuters) - "Slumdog Millionaire" was the final answer at the Critics' Choice Awards on Thursday, as the sweeping drama about an improbable winner of India's version of "Who Wants To Be a Millionaire" took the top prizes at the closely watched Oscar barometer timberwolves game . Entertainment  |  FilmThe movie, set in the terror-hit city of Mumbai, won five awards, including best picture, director (Danny Boyle) and writer (Simon Beaufoy) . It solidifies its status as an Oscar frontrunner ahead of the January 22 nominations announcement.The Critics' Choice Awards, organized by the Broadcast Film Critics Association, are one of the most reliable predictors of Oscar success Timberwolves tickets - nba .

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